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In a sub-study of CREATE, NT-pro BNP-values above 400 pg/mL predicted the need for dialysis independently of hemoglobin levels (12). Renal dysfunction increases the concentrations of both BNP and NT-proBNP (13); for this reason sequential measurements are superior to single measurements in patients with renal disease.


L’Esame. Il peptide natriuretico di tipo B (BNP) e il frammento amminoterminale del pro peptide natriuretico di tipo B (NT-proBNP) sono piccole proteine o parti di esse (peptidi), normalmente prodotte nel cuore e rilasciate in caso di sollecitazioni cardiache. Il rilascio di queste proteine è conseguente alla ritenzione di liquidi, l'aumento ...


Objectives: The role of point-of-care testing (POCT) out of hospital, especially in home care and ambulatory care settings, is an issue meriting further research. We reviewed studies reporting cardiovascular events as a result of the implementation of B-type natriuretic peptide or N-terminal pro B-type natriuretic peptide POCT (BNP/NT-proBNP POCT) for heart disease patients in the settings.
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The Stratus ® CS Acute Care™ NT-proBNP assay is an in vitro diagnostic test for the quantitative measurement of N-terminal pro-brain natriuretic peptide (NT-proBNP) in heparinized plasma. In individuals suspected of having CHF, measurements of NT-proBNP are used as an aid in diagnosis and the assessment of severity. The test is further indicated for the risk stratification of patients with ...


Lung ultrasound and blood NT-proBNP were significant predictors of CHF in a multivariate model. The LUS criterion that maximized accuracy for CHF diagnosis was presence of >1 site strongly positive for B-lines (>3 B-lines per site), resulting in sensitivity of 78.8%, specificity of 83.3%, and area under the curve (AUC) of 0.833.


A positive blood NT-proBNP test was 93.9% sensitive and 72.2% specific for the diagnosis of CHF (AUC 0.831). Conclusions and clinical importance: Point-of-care diagnostic techniques of LUS, FCU, and NT-proBNP are useful to diagnose CHF in cats with respiratory distress. bnp- und nt-probnp-wert als wichtige marker - herzberatung.


VIDAS ® NT-proBNP2 is an automated quantitative test for the determination of the N-terminal fragment of brain-type natriuretic peptide in human serum or plasma using the ELFA (Enzyme-Linked Fluorescent Assay) technique. Early diagnosis of heart failure is key to improve patient outcome.Using NT-proBNP2 can help clinicians optimize management of patients with dyspnea in the emergency room.